Mucoadhesive polymers in the treatment of dry X syndrome.

In vitro of some bfactors affecthng the adhesive strength of mucoadhesive polymers

Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the aim of this study was to evaluate the effect of four different important factors on the  mucoadhesive strength of a few  mucoadhesive polymers.am...

The Influence of Various Mucoadhesive Polymers on In Vitro Performance of the Resulting Artificial Saliva Pump Spray Formulations

The aim of this study was to investigate the rheological behavior and mucoadhesive nature of saliva substitutes, by incorporating various mucoadhesive polymers into an artificial saliva pump spray formulation. For this purpose various mucoadhesive polymers including cellulosic polymers in the range of 0.1-1.0% and Carbomers such as C974p, C971, C934p and C971 in the range of 0.01-0.1% were adde...

The Influence of Various Mucoadhesive Polymers on In Vitro Performance of the Resulting Artificial Saliva Pump Spray Formulations

The aim of this study was to investigate the rheological behavior and mucoadhesive nature of saliva substitutes, by incorporating various mucoadhesive polymers into an artificial saliva pump spray formulation. For this purpose various mucoadhesive polymers including cellulosic polymers in the range of 0.1-1.0% and Carbomers such as C974p, C971, C934p and C971 in the range of 0.01-0.1% were adde...

Phenylboronic acid modified mucoadhesive nanoparticle drug carriers facilitate weekly treatment of experimentally-induced dry eye syndrome

Propranolol Hydrochloride Buccoadhesive Tablet: Development and In-vitro Evaluation

Purposes: Propranolol HCl is a beta blocker commonly used worldwide; however, it shows a low bioavailability due to its extensive first-pass metabolism. To solve this problem, a novel drug delivery system such as buccoadhesive system might be helpful. The aim of the present investigation is to prepare the buccoadhesive tablet of propranolol HCl using different mucoadhesive polymers. Method: Buc...